Fred Hutchinson Cancer Research Center & Seattle Cancer Care Alliance

Cell Therapy Specialist

Job ID
22133
Type
Regular Full-Time
Company
Seattle Cancer Care Alliance
Location
US-WA-Seattle

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.


The Cellular Therapy Lab (CTL) at the Seattle Cancer Care Alliance (SCCA) is on the cutting edge of new technologies for cancer therapy, including cell-based immunotherapy. We are committed to advancing treatment options for our patients through the translation of innovative research into clinical practice. We collaborate with our Alliance partners (University of Washington, Fred Hutchinson Cancer Research Center and Seattle Children’s Hospital) as well as industry (biotechnology) and non-industry external entities.
 

CTL is responsible for all minimally manipulated therapeutic cell processing occurring at the SCCA for standard therapies, clinical trials and commercial cell therapeutics. Procedures range from cryopreservation to flow cytometric enumeration of cell proportions to more complex procedures such as cell selections, including enrichment and depletion. The laboratory is regulated by the FDA cGTP/cGMP standards, maintains College of American Pathologists (CAP) certification, and is accredited by the Joint Commission and FACT.

 
This posting is for a Cell Therapy Specialist I/II depending on applicable qualifications. Candidates with no previous cellular therapy experience will have hands-on training in the lab. Employees must adhere to all SCCA policies and processes, including the SCCA Code of Conduct and all HIPAA privacy requirements.

Responsibilities

Training will be provided on-site by qualified laboratory staff.  Responsibilities gradually increase from Specialist levels 1-3 and may not all apply from the list below depending on the Specialist position.

 

  • Process cellular products/specimens according to standard operating procedure (SOP), and specific guidance for clinical trials/commercial products, using aseptic technique
  • Perform and analyze results of quality control testing of components, including automated nucleated cell counts and flow cytometry
  • Prepare reagents and materials for clinical procedures
  • Enter patient and specimen information and results in the Laboratory Information Management System (LIMS)
  • Document processing steps accurately, generate processing reports and prepare patient/donor laboratory charts; review processing reports and charts
  • Understand and stay current with SOPs as needed and perform SOP qualifications. Provide input/feedback to Lab Supervisor on documentation and process improvements
  • Participate in new laboratory staff orientation, training, and competency assessments: ability to translate basic theory and practice to coach and teach other less experienced staff
  • Develop new or non-standard procedures and processes as needed
  • Assist with development and validation of equipment and processes
  • Thaw cryopreserved components and assist with infusion at the patient bedside
  • Meet unrelated donor (URD) component couriers and perform necessary testing and processing of components prior to release
  • Complete basic projects with minimal supervision
  • Builds constructive relationships across departments
  • May be asked to participate in inspections/auditing processes
  • Takes initiative to enhance scientific knowledge and acts as a technical resource in the lab
  • Takes initiative to suggest improvements/projects and participate
  • May act as subject matter expert in large, cross-department projects
  • Communicate and collaborate to share appropriate information with laboratory staff, Quality (QA), Cell Therapy Services (CTS), Administrative, Clinical Trial partners (e.g. PI and research lab staff) and additional CTP Leadership, as needed
  • Perform specialized operational duties
  • Perform cell selections:
    • CliniMACS® cell selection e.g. CD34+ cell enrichment, CD3+ cell depletion
    • Assist with bone marrow collections as an optional, more specialized function at this level

Qualifications

  • Specialist I: Bachelor’s Degree in a science-related field. Relevant experience in another drug development, manufacturing or research lab.
  • Specialist II: Bachelor’s Degree in a science-related field. 2+ years of experience in a clinical cell therapy laboratory.
  • Basic hematology and immunology knowledge
  • Knowledge of current Good Tissue Practices (cGTP) and knowledge of current Good Manufacturing Practices (cGMP).
  • Motivation and initiative to learn new scientific theory and applications
  • Mature judgment
  • Ability to work well independently
  • Proven team player, demonstrating leadership capabilities to build relationships across departments
  • Collaborate and communicate effectively across functions
  • Ability to review data thoroughly, interpret objectively, communicate and discuss with others
  • Strong troubleshooting capabilities for both standard and complex (e.g. clinical trial) processes
  • Scientific writing skills, including preparation of clear, concise SOPs and technical reports
  • Strong math skills
  • Strong communication skills, both oral and written, including the ability to describe results to CTP Leadership and Principal Investigators
  • Flexibility in scheduling: nights, weekends, holidays and on-call rotations
  • Bachelor’s Degree in a science-related field preferred

 

SCCA has a mandatory COVID-19 vaccination policy, and there are no exceptions for any employee who is patient-facing and/or requires access to SCCA facilities.

Exceptions exist only for employees whose positions are fully remote, with no required access to campus. As a condition of employment, newly hired employees requiring access to campus must provide proof of vaccination before their first day of employment.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

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