Fred Hutchinson Cancer Research Center & Seattle Cancer Care Alliance

Cell Therapy Specialist I-III

Job ID
20408
Type
Regular Full-Time
Company
Seattle Cancer Care Alliance
Location
US-WA-Seattle

Overview

The Seattle Cancer Care Alliance (SCCA), located in Seattle, Washington, is part of a dynamic collaboration among three organizations known nationally and internationally for their patient care and research: Fred Hutchinson Cancer Research Center, University of Washington, and Seattle Children's. Over the past 25 years, these institutions have worked together to support their mission of adult and pediatric oncology patient care services, research and education.


The Cellular Therapy Lab (CTL) at the Seattle Cancer Care Alliance (SCCA) is on the cutting edge of new technologies for cancer therapy, including cell-based immunotherapy. We are committed to advancing treatment options for our patients through the translation of innovative research into clinical practice. We collaborate with our Alliance partners (University of Washington, Fred Hutchinson Cancer Research Center and Seattle Children’s Hospital) as well as industry (biotechnology) and non-industry external entities.
 

CTL is responsible for all minimally manipulated therapeutic cell processing occurring at the SCCA for standard therapies, clinical trials and commercial cell therapeutics. Procedures range from cryopreservation to flow cytometric enumeration of cell proportions to more complex procedures such as cell selections, including enrichment and depletion. The laboratory is regulated by the FDA cGTP/cGMP standards, maintains College of American Pathologists (CAP) certification, and is accredited by the Joint Commission and FACT.

 
This posting is for a Cell Therapy Specialist I/II/III depending on applicable qualifications. Candidates with no previous cellular therapy experience will have hands-on training in the lab. Employees must adhere to all SCCA policies and processes, including the SCCA Code of Conduct and all HIPAA privacy requirements.

 

Work Schedule: T-F, 5:00pm-3:30am (Night Shift)

Responsibilities

Training will be provided on-site by qualified laboratory staff.  Responsibilities gradually increase from Specialist levels 1-3 and may not all apply from the list below depending on the Specialist position.

 

  • Process cellular products/specimens according to standard operating procedure (SOP), and specific guidance for clinical trials/commercial products, using aseptic technique
  • Perform and analyze results of quality control testing of components, including automated nucleated cell counts and flow cytometry
  • Prepare reagents and materials for clinical procedures
  • Enter patient and specimen information and results in the Laboratory Information Management System (LIMS)
  • Document processing steps accurately, generate processing reports and prepare patient/donor laboratory charts; review processing reports and charts
  • Understand and stay current with SOPs as needed and perform SOP qualifications. Provide input/feedback to Lab Supervisor on documentation and process improvements
  • Participate in new laboratory staff orientation, training, and competency assessments: ability to translate basic theory and practice to coach and teach other less experienced staff
  • Develop new or non-standard procedures and processes as needed
  • Assist with development and validation of equipment and processes
  • Thaw cryopreserved components and assist with infusion at the patient bedside
  • Meet unrelated donor (URD) component couriers and perform necessary testing and processing of components prior to release
  • Complete basic projects with minimal supervision
  • Builds constructive relationships across departments
  • May be asked to participate in inspections/auditing processes
  • Takes initiative to enhance scientific knowledge and acts as a technical resource in the lab
  • Takes initiative to suggest improvements/projects and participate
  • May act as subject matter expert in large, cross-department projects
  • Communicate and collaborate to share appropriate information with laboratory staff, Quality (QA), Cell Therapy Services (CTS), Administrative, Clinical Trial partners (e.g. PI and research lab staff) and additional CTP Leadership, as needed
  • Perform specialized operational duties
  • Perform cell selections:
    • CliniMACS® cell selection e.g. CD34+ cell enrichment, CD3+ cell depletion
    • Assist with bone marrow collections as an optional, more specialized function at this level
  • The CTL Specialist Night Shift position will primarily be responsible for the receipt, processing, and coordination of unrelated donor products that arrive in the Cellular Therapy Lab between the hours of 8pm and 3:30am.
  • The Night Shift position will also be responsible for the placement of cryopreserved product bags into long term storage along with urgent bag checks, infusion preparation, and priority chart review. 

Qualifications

Required:

  • Specialist I: Bachelor’s Degree or equivalent. Relevant experience in another drug development, manufacturing or research lab.
  • Specialist II: Bachelor’s Degree in a science-related field preferred. 2+ years of experience in a clinical cell therapy laboratory.
  • Specialist III: Bachelor’s Degree in a science-related field preferred. 5+ years of experience in a clinical cell therapy laboratory with increasing responsibility.
  • Basic hematology knowledge
  • Motivation and initiative to learn new scientific theory and applications
  • Mature judgment
  • Work independently with moderate supervision
  • Proven team player
  • Collaborate and communicate effectively across functions
  • Interpret data thoroughly
  • Strong trouble-shooting capabilities
  • Scientific writing skills, including preparation of clear, concise SOPs and technical reports
  • Strong math skills
  • Strong communication skills
  • Attention to detail
  • Flexibility in scheduling: night, weekend, holiday and on-call rotations

Preferred:

  • Flow cytometry expertise
  • Immunotherapy experience
  • CliniMACS® operation experience
  • LabWare, LIMS knowledge
  • A good understanding of cGMP/cGTP standards
  • Advanced knowledge of oncology, hematology and/or immunology
  • Flow cytometry expertise
  • Immunotherapy experience
  • CliniMACS® operation experience
  • Surgical tech experience
  • LabWare LIMS knowledge
  • A good understanding of cGMP/cGTP standards
  • Proven record of completing projects efficiently and effectively

 

SCCA has a mandatory COVID-19 vaccination policy, and there are no exceptions for any employee who is patient-facing and/or requires access to SCCA facilities.

Exceptions exist only for employees whose positions are fully remote, with no required access to campus. As a condition of employment, newly hired employees requiring access to campus must provide proof of vaccination before their first day of employment.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

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