The Seattle Cancer Care Alliance (SCCA), located in Seattle, Washington, is part of a dynamic collaboration among three organizations known nationally and internationally for their patient care and research: Fred Hutchinson Cancer Research Center, University of Washington, and Seattle Children's. Over the past 25 years, these institutions have worked together to support their mission of adult and pediatric oncology patient care services, research and education.
Cellular Therapeutics (CTP) is comprised of four functional groups with responsibility for the production of clinical cellular products for patient treatment: Apheresis Unit at SCCA, Cellular Therapy Laboratory (CTL), Quality Assurance (QA), and Cellular Therapy Services (CTS).
The Senior Manager, Cellular Therapeutics role is an integral part of the CTP leadership team. This position is expected to bridge departmental operations, scientific direction and administration, provide continuous connection between individual services within CTP, working in a collaborative relationship with SCCA leadership toward a shared mission and vision.
The CTL is responsible for all minimally manipulated therapeutic cell processing occurring at the SCCA for both standard therapies and clinical trials including immunotherapies. Procedures range from cryopreservation and flow cytometric enumeration of cell proportions to more complex procedures such as cell selection, enrichment, and depletion for manufacture of immunotherapies. In addition, CTL stores and prepares for infusion a variety of externally manufactured cell-based therapeutics, including FDA Approved CAR T cells. The CTL is regulated by the FDA cGTP/cGMP standards, maintain College of American Pathologists (CAP) certification, and is accredited by the Foundation for the Accreditation of Cellular Therapy (FACT).
The nature of this work is challenging, and the position requires individual initiative and decision-making capabilities to carry out the required tasks. The work requires mature judgment for the development of appropriate technical, scientific and business initiatives and in recognizing circumstances requiring special attention. Flexibility in scheduling is required. Interaction with other departments and laboratories in the SCCA, Fred Hutch Clinical Research Division, UW Medical Center and external organizations/institutions is inherent to the position. The position requires excellent written and verbal communication skills.